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Mitochondrial dysfunction is associated with abdominal obesity and insulin resistance. (Not the content or amount of mitochondria, as has been previously suggested.)
J Clin Endocrinol Metab. 2010 Apr 9. [Epub ahead of print]
Muscle Mitochondrial Oxidative Phosphorylation Activity, But Not Content, Is Altered with Abdominal Obesity in Sedentary Men: Synergism with Changes in Insulin Sensitivity. Read Abstract