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The obesity-related impairment of protein metabolism is characterized by
1) a reduced turnover rate of skeletal muscle proteins in PA
2) a lack of stimulation of mitochondrial protein synthesis by insulin and amino acid; and
3) less inhibition of WB proteolysis by insulin and amino acid. J Clin Endocrinol Metab. 2009 Aug;94(8):3044-50. Epub 2009 May 26.